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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 22.73
Human Site: Y66 Identified Species: 31.25
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 Y66 D K S S R K T Y T F D M V F G
Chimpanzee Pan troglodytes XP_507923 1056 119132 Y66 D K S S R K T Y T F D M V F G
Rhesus Macaque Macaca mulatta XP_001087644 853 96218
Dog Lupus familis XP_534964 1334 149091 Y348 D K S S R K T Y T F D M V F G
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 Y65 D K T S K K T Y T F D M V F G
Rat Rattus norvegicus O55165 796 89797
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 Y53 D K A F T Y D Y V F D P S V E
Frog Xenopus laevis P28025 1060 119314 Y59 D K L G K K T Y T F D M V F G
Zebra Danio Brachydanio rerio NP_775368 955 106984 E31 C R P F N T V E R K S G S H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 F64 D S K L T K K F T F D R S F G
Honey Bee Apis mellifera XP_623508 706 80766
Nematode Worm Caenorhab. elegans P46873 699 78760
Sea Urchin Strong. purpuratus P46872 699 78679
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 F89 N K Q I D R T F L F D K V F G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 F59 G K H I D R V F T F D K V F G
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 Y102 Y S S S K K T Y Q F D Q V F G
Red Bread Mold Neurospora crassa P48467 928 102392
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 0 100 N.A. 86.6 0 N.A. N.A. 33.3 80 0 N.A. 46.6 0 0 0
P-Site Similarity: 100 100 0 100 N.A. 100 0 N.A. N.A. 40 86.6 6.6 N.A. 53.3 0 0 0
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 46.6 N.A. N.A. 46.6 66.6 0
P-Site Similarity: 66.6 N.A. N.A. 60 73.3 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 42 0 0 0 12 0 6 0 0 0 59 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 6 % E
% Phe: 0 0 0 12 0 0 0 18 0 59 0 0 0 53 0 % F
% Gly: 6 0 0 6 0 0 0 0 0 0 0 6 0 0 53 % G
% His: 0 0 6 0 0 0 0 0 0 0 0 0 0 6 0 % H
% Ile: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 48 6 0 18 42 6 0 0 6 0 12 0 0 0 % K
% Leu: 0 0 6 6 0 0 0 0 6 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 30 0 0 0 % M
% Asn: 6 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 6 0 0 0 0 0 0 0 0 6 0 0 0 % P
% Gln: 0 0 6 0 0 0 0 0 6 0 0 6 0 0 0 % Q
% Arg: 0 6 0 0 18 12 0 0 6 0 0 6 0 0 0 % R
% Ser: 0 12 24 30 0 0 0 0 0 0 6 0 18 0 0 % S
% Thr: 0 0 6 0 12 6 42 0 42 0 0 0 0 0 6 % T
% Val: 0 0 0 0 0 0 12 0 6 0 0 0 48 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 0 0 0 6 0 42 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _